[Nationwide survey on susceptibilities of clinical isolates from urinary tract to antimicrobial agents in Japan, 1991].

This study was conducted to investigate susceptibilities of urinary tract isolates to antimicrobial agents examined at 123 hospital laboratories in Japan from September to December in 1991. In this study, identification and susceptibility testing were carried out at each laboratory. The susceptibility testing was performed according to the disk diffusion method recommended by National Committee for Clinical Laboratory Standards. MRSA showed high resistance rates to all agents tested except to minocycline (MINO). MSSA had good susceptibility to imipenem (IPM) and cephalosporins with susceptibility rates higher than 90%. Enterococcus faecalis was susceptible to IPM, ampicillin and piperacillin (PIPC) and highly resistant to cephalosporins, gentamicin (GM), erythromycin, clindamycin and MINO. Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis were susceptible to beta-lactam drugs, GM and ofloxacin (OFLX). High susceptibility rates were observed for strains of Enterobacter cloacae, Citrobacter freundii to IPM, GM, and OFLX and of Serratia marcescens for IPM and GM. Pseudomonas aeruginosa strains were highly susceptible to IPM, ceftazidime, AMK, cefsulodin, cefoperazone, PIPC in this order.