Danese D, Sciacchitano S
II Cattedra di Endocrinologia, Università degli Studi di Roma La Sapienza.
Minerva Endocrinol. 1993 Sep;18(3):129-37.
Thyroid nodule is extremely common. Its prevalence has been estimated to be more than 5% in the adult population. If thyroid nodule is a rare condition, 0.004% a year, identifying those nodules, which are likely to be malignant, is very important for physicians. The evaluation of thyroid is carried out using the fine needle aspiration biopsy (FNAB), the ultrasonography, and scanning with 131I and 99Tc. Before FNAB thyroid scans was the most common test in clinical evaluation of thyroid nodules, used to identify "hot" and "cold" lesions. Hot or warm nodules, about 5%, are seldom malignant, whereas cold or hypofunctional have a 10% to 25% chances of being malignant. FNAB is the elected laboratory test: this procedure is easily, simple, non traumatic, and very acceptable to the patients. Ultrasound is useful in several settings: it provides a non invasive and relatively inexpensive means of following the size of nodule, after medical therapy and FNAB.
甲状腺结节极为常见。据估计,其在成年人群中的患病率超过5%。如果甲状腺结节是一种罕见病症,每年发病率为0.004%,那么识别那些可能为恶性的结节对医生来说非常重要。甲状腺评估通过细针穿刺活检(FNAB)、超声检查以及131I和99Tc扫描来进行。在FNAB之前,甲状腺扫描是甲状腺结节临床评估中最常用的检查,用于识别“热”性和“冷”性病变。热结节或温结节约占5%,很少为恶性,而冷结节或功能减退结节有10%至25%的恶变几率。FNAB是首选的实验室检查:该操作简便、简单、无创,且患者非常容易接受。超声在多种情况下都很有用:它提供了一种非侵入性且相对廉价的方法,用于在药物治疗和FNAB后跟踪结节大小。