Abramov Iu B, Rybakova L V, Sachkov V I
Anesteziol Reanimatol. 1993 Nov-Dec(6):11-4.
Tactile and pain thresholds were determined in 116 patients 24 hours before surgery upon premedication and administration of fentanyl and droperidol during induction to anesthesia. Statistical correlation analysis has shown that high pain thresholds in patients 24 hours before surgery indicate low consumption of barbiturates during induction to anesthesia, high efficacy of drugs used for NLA, and infrequent reactions to intubation irrespective of the efficacy of premedication. Low pain thresholds after premedication predict low efficacy of drugs for NLA and high consumption of fentanyl during surgery.
在116例患者手术前24小时，于术前用药以及麻醉诱导期间给予芬太尼和氟哌利多后，测定其触觉和疼痛阈值。统计相关性分析表明，手术前24小时患者的高疼痛阈值表明麻醉诱导期间巴比妥类药物的消耗量低、用于神经安定镇痛麻醉（NLA）的药物疗效高，并且无论术前用药效果如何，插管反应均不常见。术前用药后疼痛阈值低预示着用于NLA的药物疗效低以及手术期间芬太尼的高消耗量。
