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默西塞德郡接触煤尘和空气污染的学童的呼吸道发病率

Respiratory morbidity in Merseyside schoolchildren exposed to coal dust and air pollution.

作者信息

Brabin B, Smith M, Milligan P, Benjamin C, Dunne E, Pearson M

机构信息

Liverpool School of Tropical Medicine.

出版信息

Arch Dis Child. 1994 Apr;70(4):305-12. doi: 10.1136/adc.70.4.305.

Abstract

A cross sectional study was carried out to determine whether schoolchildren in a specific locality exposed to pollution from steam coal dust have an excess of respiratory symptoms compared with children in control areas. A total of 1872 primary schoolchildren (aged 5-11 years) from five primary schools in the Bootle dock area of Liverpool (exposed area), five primary schools in South Sefton (control area), and five primary schools in Wallasey (control area) were studied. A questionnaire was distributed through the schools and was completed by the parents of the children. The questionnaire inquired about respiratory symptoms (cough, wheezing, and shortness of breath), allergy, atopy, smoking, and socioeconomic factors. Height, weight, and peak expiratory flow were measured. Compliance was good (92%) and similar in the three study areas. The children in the three areas were of similar mean age (7.5 years), height (1.24 m), sex ratio, and had a similar prevalence of paternal (6.2%) and maternal (7%) asthma. The exposed zone contained more unemployed parents (41, 29, and 29% respectively), more rented housing (64, 45, 34%), and more smoking parents (71, 60, 59%) than the control areas. Respiratory symptoms were significantly more common in the exposed area, including wheeze (25.0, 20.6, and 17.5%), excess cough (40.0, 23.4, and 25.1%), and school absences for respiratory symptoms (47.5, 35.9, and 34.9%). These differences remained significant even if the groups were subdivided according to whether or not parents smoked or were employed. Multiple logistic regression analysis confirmed the exposed zone as a significant risk factor for absenteeism from school due to respiratory symptoms (odds ratio 1.55, 95% confidence interval 1.17 to 2.06) after adjusting for confounding factors. Standard dust deposit gauges on three schools confirmed a significantly higher dust burden in the exposed zone. An increased prevalence of respiratory symptoms in primary schoolchildren exposed to coal dust is confirmed. Although the association with known coal dust pollution is suggestive a cross sectional study cannot confirm a casual relation and further studies are needed.

摘要

开展了一项横断面研究,以确定特定地区暴露于蒸汽煤尘污染的学童与对照地区的儿童相比,呼吸道症状是否更多。对来自利物浦布特尔码头地区五所小学(暴露地区)、南塞夫顿五所小学(对照地区)和沃勒西五所小学(对照地区)的1872名小学生(5 - 11岁)进行了研究。通过学校发放问卷,由儿童的家长填写。问卷询问了呼吸道症状(咳嗽、喘息和呼吸急促)、过敏、特应性、吸烟情况以及社会经济因素。测量了身高、体重和呼气峰值流速。问卷回复率良好(92%),且在三个研究地区相似。三个地区儿童的平均年龄(7.5岁)、身高(1.24米)、性别比例相似,父亲(6.2%)和母亲(7%)患哮喘的患病率也相似。与对照地区相比,暴露地区失业父母更多(分别为41%、29%和29%),租房居住的更多(分别为64%、45%、34%),吸烟的父母更多(分别为71%、60%、59%)。呼吸道症状在暴露地区明显更常见,包括喘息(分别为25.0%、20.6%和17.5%)、过度咳嗽(分别为40.0%、23.4%和25.1%)以及因呼吸道症状缺课(分别为47.5%、35.9%和34.9%)。即使根据父母是否吸烟或就业对分组进行细分,这些差异仍然显著。多因素逻辑回归分析证实,在调整混杂因素后,暴露地区是因呼吸道症状缺课的显著危险因素(比值比1.55,95%置信区间1.17至2.06)。三所学校的标准灰尘沉积测量仪证实暴露地区的灰尘负担明显更高。暴露于煤尘的小学生呼吸道症状患病率增加得到了证实。尽管与已知煤尘污染的关联具有提示性,但横断面研究无法证实因果关系,还需要进一步研究。

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