Doull I J, Williams A A, Freezer N J, Holgate S T
University Medicine, Southampton General Hospital, UK.
Thorax. 1996 Jun;51(6):630-1. doi: 10.1136/thx.51.6.630.
Respiratory symptoms such as cough and wheeze are associated with significant morbidity, including school absenteeism.
A respiratory questionnaire was sent to the parents of all 5727 children aged 7-9 years of age registered with 95 general practitioners in the Southampton area to determine (a) the prevalence of asthma, cough and wheeze, (b) the effects of respiratory symptoms on school absenteeism, and (c) the use of anti-asthma medication.
A total of 4830 parents replied (response rate 86%). The 12 month prevalence of wheeze in the absence of cough was 5.5%, cough in the absence of wheeze was 10.0%, and 7.6% reported cough and wheeze; 15.2% of children had been diagnosed. Of the 4830 who replied, 12.7% were receiving bronchodilators, 0.6% xanthine derivatives, 1.7% sodium cromoglycate, and 4.1% inhaled corticosteroids. In all, 348 (7.2%) children had missed more than five days of schooling in the preceding year for respiratory symptoms, while 43 children (0.9%) had missed more than 20 days of schooling in the preceding year. Of the children who had missed more than five days of schooling, 43% reported cough and wheeze, 33% cough alone, and 16% wheeze alone in the preceding year. Compared with children who coughed, those who wheezed were significantly more likely to be diagnosed as asthmatic and to be receiving bronchodilators or inhaled corticosteroids.
In this study, cough was the most frequently reported symptom amongst children missing more than five days of schooling per year.
咳嗽和喘息等呼吸道症状与包括缺课在内的严重发病率相关。
向南安普顿地区95名全科医生登记的所有5727名7至9岁儿童的家长发送了一份呼吸道问卷,以确定(a)哮喘、咳嗽和喘息的患病率,(b)呼吸道症状对缺课的影响,以及(c)抗哮喘药物的使用情况。
共有4830名家长回复(回复率86%)。无咳嗽时喘息的12个月患病率为5.5%,无喘息时咳嗽的患病率为10.0%,报告咳嗽和喘息的患病率为7.6%;15.2%的儿童已被诊断。在回复的4830人中,12.7%正在接受支气管扩张剂治疗,0.6%接受黄嘌呤衍生物治疗,1.7%接受色甘酸钠治疗,4.1%接受吸入性糖皮质激素治疗。总共有348名(7.2%)儿童在前一年因呼吸道症状缺课超过五天,而43名儿童(0.9%)在前一年缺课超过20天。在前一年缺课超过五天的儿童中,43%报告有咳嗽和喘息,33%仅咳嗽,16%仅喘息。与咳嗽的儿童相比,喘息的儿童被诊断为哮喘以及接受支气管扩张剂或吸入性糖皮质激素治疗的可能性显著更高。
在本研究中,咳嗽是每年缺课超过五天的儿童中最常报告的症状。