Lewińska D, Rosiński S, Piatkiewicz W
Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw.
Artif Organs. 1994 Mar;18(3):217-22. doi: 10.1111/j.1525-1594.1994.tb02179.x.
A new material, natural polysaccharide-pectin, was tested for removal of human blood lipoproteins. Pectin was prepared in a granular form with the help of the specifically designed gelification device and tested in batch sorption experiments in vitro for removal of total cholesterol (TC), LDL-cholesterol (LDL-C), and HDL-cholesterol (HDL-C) from human plasma. Pectin granules removed 40% of TC, 45% of LDL-C, and 36% of HDL-C on average with respect to the initial amounts whereas corresponding values for LA-40 Kanegafuchi adsorbent were 69%, 81%, and 33% in the same experimental conditions (shaking 1 g of sorbent sample with 2 ml of plasma).
一种新型材料——天然多糖果胶,被用于测试其去除人体血液中脂蛋白的能力。果胶借助专门设计的凝胶化装置制备成颗粒状,并在体外分批吸附实验中进行测试,以从人血浆中去除总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)。相对于初始量,果胶颗粒平均去除了40%的TC、45%的LDL-C和36%的HDL-C,而在相同实验条件下(将1 g吸附剂样品与2 ml血浆振荡混合),LA-40 钟渊化学吸附剂的相应去除率分别为69%、81%和33%。