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Metabolism of 2,5,2' -trichloro-, 2,5,2',5' -tetrachloro-, and 2,4,5,2',5' -pentachlorobiphenyl in rat hepatic microsomal systems.

作者信息

Ghiasuddin S M, Menzer R E, Nelson J O

出版信息

Toxicol Appl Pharmacol. 1976 Apr;36(1):187-94. doi: 10.1016/0041-008x(76)90038-7.

DOI:10.1016/0041-008x(76)90038-7
PMID:818740
Abstract
摘要

相似文献

1
Metabolism of 2,5,2' -trichloro-, 2,5,2',5' -tetrachloro-, and 2,4,5,2',5' -pentachlorobiphenyl in rat hepatic microsomal systems.大鼠肝微粒体系统中2,5,2'-三氯联苯、2,5,2',5'-四氯联苯和2,4,5,2',5'-五氯联苯的代谢
Toxicol Appl Pharmacol. 1976 Apr;36(1):187-94. doi: 10.1016/0041-008x(76)90038-7.
2
Induction of both 3-methylcholanthrene- and phenobarbitone-type microsomal enzyme activity by a single polychlorinated biphenyl isomer.
Biochem Pharmacol. 1980 Feb;29(2):259-62. doi: 10.1016/0006-2952(80)90339-1.
3
Hepatic microsomal enzyme induction by 2,2', 3,3', 4,4'- and 2,2', 3', 4,4', 5-hexachlorobiphenyl.2,2',3,3',4,4'-六氯联苯和2,2',3',4,4',5-六氯联苯对肝微粒体酶的诱导作用
Life Sci. 1980 Dec 15;27(24):2333-7. doi: 10.1016/0024-3205(80)90502-0.
4
The induction of hepatic microsomal metabolism in rats following acute administration of a mixture of polybrominated biphenyls.急性给予多溴联苯混合物后大鼠肝脏微粒体代谢的诱导作用。
Toxicol Appl Pharmacol. 1976 Nov;38(2):237-49. doi: 10.1016/0041-008x(76)90132-0.
5
Covalent binding in vitro of polychlorinated biphenyls to microsomal macromolecules. Involvement of metabolic activation by a cytochrome P-450-linked mono-oxygenase system.多氯联苯在体外与微粒体大分子的共价结合。细胞色素P - 450连接的单加氧酶系统参与代谢激活。
Biochem Pharmacol. 1978 Feb 15;27(4):585-93. doi: 10.1016/0006-2952(78)90399-4.
6
Polychlorinated biphenyls as phenobarbitone-type inducers of microsomal enzymes. Structure-activity relationships for a series of 2,4-dichloro-substituted congeners.多氯联苯作为微粒体酶的苯巴比妥型诱导剂。一系列2,4-二氯取代同系物的构效关系。
Biochem Pharmacol. 1983 Oct 1;32(19):2955-63. doi: 10.1016/0006-2952(83)90402-1.
7
Time-course of induction of microsomal enzymes following treatment with polychlorinated biphenyl.多氯联苯处理后微粒体酶诱导的时间进程。
Bull Environ Contam Toxicol. 1974 Mar;11(3):206-12. doi: 10.1007/BF01685093.
8
3,4,5,3',4'-Pentachlorobiphenyl as a useful inducer for purification of rat liver microsomal cytochrome P448.
Biochem Biophys Res Commun. 1979 Dec 14;91(3):1140-7. doi: 10.1016/0006-291x(79)91999-5.
9
Polychlorinated biphenyls. The effect of structure on the induction of quail hepatic microsomal enzymes.
Toxicol Appl Pharmacol. 1978 Mar;43(3):507-18. doi: 10.1016/s0041-008x(78)80010-6.
10
Polychlorinated naphthalenes as hepatic microsomal enzyme inducers in the immature male rat.
Gen Pharmacol. 1981;12(2):83-7. doi: 10.1016/0306-3623(81)90103-8.

引用本文的文献

1
Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2',5'-Tetrachlorobiphenyl.人细胞色素P450 2A6以及猴细胞色素P450 2A24和2A26酶在2,5,2',5'-四氯联苯氧化中的作用
Drug Metab Dispos. 2016 Dec;44(12):1899-1909. doi: 10.1124/dmd.116.072991. Epub 2016 Sep 13.
2
Effects of polychlorinated biphenyls on liver regeneration in the rat: influence of position and degree of chlorination.多氯联苯对大鼠肝脏再生的影响：氯化位置和程度的影响。
Arch Environ Contam Toxicol. 1982;11(2):239-44. doi: 10.1007/BF01054902.
3
Distribution of polychlorobiphenyls in pregnant mice and fetuses on various days of gestation.
多氯联苯在妊娠不同天数的孕鼠和胎儿中的分布。
Arch Environ Contam Toxicol. 1981;10(3):289-96. doi: 10.1007/BF01055630.
4
Comparative metabolism of PCB isomers by three species of fish and the rat.
Bull Environ Contam Toxicol. 1977 Nov;18(5):631-9. doi: 10.1007/BF01684011.
5
Studies on the microsomal metabolism and binding of polybrominated biphenyls (PBBs).多溴联苯的微粒体代谢及结合研究
Environ Health Perspect. 1978 Apr;23:51-61. doi: 10.1289/ehp.782351.