• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

α干扰素治疗丙型肝炎病毒感染相关冷球蛋白血症的长期疗效

Long-term results of therapy with interferon alpha for cryoglobulinemia associated with hepatitis C virus infection.

作者信息

Durand J M, Cretel E, Kaplanski G, Lefevre P, Retornaz F, Soubeyrand J

机构信息

Department of Internal Medicine, CHU de Sainte-Marguerite, Marseille, France.

出版信息

Clin Rheumatol. 1994 Mar;13(1):123-5. doi: 10.1007/BF02229881.

DOI:10.1007/BF02229881
PMID:8187434
Abstract

We describe the long term results of treatment with interferon (IFN) in two patients with cryoglobulinemia and chronic hepatitis related to Hepatitis C virus (HCV). Our results suggest that interferon may induce long remission in cryoglobulinemia associated with HCV infection and that the effect of IFN is not dependent on the effect on liver function, but results of its antiviral activity.

摘要

我们描述了用干扰素(IFN)治疗两名患有冷球蛋白血症及与丙型肝炎病毒(HCV)相关的慢性肝炎患者的长期结果。我们的结果表明,干扰素可能诱导与HCV感染相关的冷球蛋白血症长期缓解,且干扰素的作用并不取决于其对肝功能的影响,而是其抗病毒活性的结果。

相似文献

1
Long-term results of therapy with interferon alpha for cryoglobulinemia associated with hepatitis C virus infection.α干扰素治疗丙型肝炎病毒感染相关冷球蛋白血症的长期疗效
Clin Rheumatol. 1994 Mar;13(1):123-5. doi: 10.1007/BF02229881.
2
Dramatic worsening of hepatitis C virus-related cryoglobulinemia subsequent to treatment with interferon alfa.使用干扰素α治疗后丙型肝炎病毒相关冷球蛋白血症急剧恶化。
JAMA. 1995 Jul 12;274(2):126. doi: 10.1001/jama.1995.03530020044018.
3
Prevalence of cryoglobulinemia in chronic hepatitis C virus infection and response to treatment with interferon-alpha.慢性丙型肝炎病毒感染中冷球蛋白血症的患病率及对α干扰素治疗的反应
J Clin Gastroenterol. 1997 Dec;25(4):612-8. doi: 10.1097/00004836-199712000-00013.
4
Interferon/pegylated interferon and ribavirin in HCV-associated kidney disease with or without cryoglobulinemia.干扰素/聚乙二醇化干扰素与利巴韦林用于治疗伴有或不伴有冷球蛋白血症的丙型肝炎病毒相关性肾病。
J Hepatol. 2006 Feb;44(2):432-3; author reply 433. doi: 10.1016/j.jhep.2005.10.020. Epub 2005 Nov 21.
5
Mixed cryoglobulinaemia and hepatitis C virus infection.混合性冷球蛋白血症与丙型肝炎病毒感染
Ital J Gastroenterol Hepatol. 1997 Dec;29(6):579.
6
Antiviral therapy of symptomatic HCV-mixed cryoglobulinemia after liver transplant: case report and literature review.肝移植后有症状的丙型肝炎病毒混合性冷球蛋白血症的抗病毒治疗:病例报告及文献综述
Int J Artif Organs. 2013 May 17;36(5):367-72. doi: 10.5301/ijao.5000199. Epub 2013 Feb 28.
7
Effect of alpha-interferon on hepatitis C virus chronic infection in mixed cryoglobulinemia patients.α干扰素对混合性冷球蛋白血症患者丙型肝炎病毒慢性感染的影响。
Infection. 1993 Mar-Apr;21(2):93-7. doi: 10.1007/BF01710739.
8
[Can alpha-interferon exacerbate a case of mixed cryoglobulinemia?].[α干扰素会加重混合性冷球蛋白血症病情吗?]
Recenti Prog Med. 1992 Nov;83(11):654-5.
9
Pattern of HCV antibodies with special reference to NS5A reactivity in HCV-infected patients: relation to viral genotype, cryoglobulinemia and response to interferon.
J Hepatol. 1998 Apr;28(4):538-43. doi: 10.1016/s0168-8278(98)80275-4.
10
Long-term effect of HCV eradication in patients with mixed cryoglobulinemia: a prospective, controlled, open-label, cohort study.慢性丙型肝炎病毒感染患者混合性冷球蛋白血症的长期疗效:一项前瞻性、对照、开放标签、队列研究。
Hepatology. 2015 Apr;61(4):1145-53. doi: 10.1002/hep.27623. Epub 2015 Feb 10.

引用本文的文献

1
Fatal exacerbation of hepatitis C-related cryoglobulinemia with interferon-alpha therapy.
Dig Dis Sci. 1999 Jul;44(7):1364-5. doi: 10.1023/a:1026691416498.

本文引用的文献

1
Cryoglobulinemia with vasculitis associated with hepatitis C virus infection.丙型肝炎病毒感染相关的冷球蛋白血症伴血管炎
Gastroenterology. 1993 Jan;104(1):272-7. doi: 10.1016/0016-5085(93)90862-7.
2
Effect of interferon-alpha on immunoglobulin synthesis by human B cells.α干扰素对人B细胞免疫球蛋白合成的影响。
J Immunol. 1986 Nov 15;137(10):3153-7.
3
Hepatitis C virus in patients with cryoglobulinemia type II.II型冷球蛋白血症患者中的丙型肝炎病毒
J Infect Dis. 1990 Aug;162(2):569-70. doi: 10.1093/infdis/162.2.569.
4
Detection of hepatitis C viral sequences in blood donations by "nested" polymerase chain reaction and prediction of infectivity.通过“巢式”聚合酶链反应检测献血中的丙型肝炎病毒序列及感染性预测
Lancet. 1990 Jun 16;335(8703):1419-22. doi: 10.1016/0140-6736(90)91446-h.
5
Mixed cryoglobulinemia responsive to interferon-alpha.对干扰素-α有反应的混合性冷球蛋白血症
Am J Med. 1991 Nov;91(5):554-5. doi: 10.1016/0002-9343(91)90196-5.
6
Long-term results of therapy with interferon-alpha for type II essential mixed cryoglobulinemia.α-干扰素治疗II型原发性混合性冷球蛋白血症的长期疗效
Blood. 1991 Dec 15;78(12):3142-7.
7
Effect of interferon-alpha 2b on cryoglobulinemia related to hepatitis C virus infection.干扰素-α 2b对丙型肝炎病毒感染相关冷球蛋白血症的影响。
J Infect Dis. 1992 Apr;165(4):778-9. doi: 10.1093/infdis/165.4.778.
8
Low-dose interferon-alpha for mixed cryoglobulinemia associated with hepatitis C virus.低剂量α干扰素治疗丙型肝炎病毒相关的混合性冷球蛋白血症
Am J Med. 1992 Oct;93(4):476. doi: 10.1016/0002-9343(92)90185-e.
9
A role for hepatitis C virus infection in type II cryoglobulinemia.丙型肝炎病毒感染在Ⅱ型冷球蛋白血症中的作用。
N Engl J Med. 1992 Nov 19;327(21):1490-5. doi: 10.1056/NEJM199211193272104.