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一例与良好预后相关的极其巨大的菜花型卵巢癌皮肤转移瘤。

An extremely large, cauliflower-type, cutaneous metastasis of ovarian cancer associated with good prognosis.

作者信息

Traiman P, de Luca L A, Bacchi C E

机构信息

State University of São Paulo, Department of Gynecology & Obstetrics, Brazil.

出版信息

Gynecol Oncol. 1994 May;53(2):239-41. doi: 10.1006/gyno.1994.1122.

Abstract

We report an unusual case of a 37-year-old woman who presented in 1980 with a serous papillary cystadenocarcinoma of the ovary. The patient refused any treatment and the patient was lost to follow-up for 6 years. After this period of time she returned with an extremely large, cutaneous, cauliflower-type of metastasis located in the lower abdominal wall and measuring 20 x 20 cm. She received two courses of chemotherapy treatment consisting of intraperitoneal cisplatin (100 mg/m2) and intravenous epirubicin (50 mg/m2) every 3 weeks. After the second course of chemotherapy she received cobalt radiotherapy (5000 cGy). Subsequently, she received four more courses of chemotherapy with dramatic remission of the cutaneous metastasis. Shortly after chemotherapy, the patient underwent a laparotomy consisting of the resection of the abdominal wall including the cutaneous metastasis completed by total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy. The patient is well after the surgery and without any evidence of residual disease after 6 years of follow up. This description illustrates a rare example of ovarian cancer with skin metastases and favorable outcome.

摘要

我们报告了一例罕见病例,一名37岁女性于1980年被诊断为卵巢浆液性乳头状囊腺癌。患者拒绝任何治疗,失访6年。6年后她回来时,下腹部壁出现了一个极其巨大的、皮肤型的菜花状转移灶,大小为20×20厘米。她接受了两个疗程的化疗,每3周进行一次腹腔内顺铂(100mg/m²)和静脉注射表柔比星(50mg/m²)治疗。第二个疗程化疗后,她接受了钴放疗(5000cGy)。随后,她又接受了四个疗程的化疗,皮肤转移灶显著缓解。化疗后不久,患者接受了剖腹手术,包括切除腹壁及皮肤转移灶,同时进行了全腹子宫切除术、双侧输卵管卵巢切除术和大网膜切除术。术后患者恢复良好,随访6年无任何残留疾病迹象。本病例描述了一例罕见的伴有皮肤转移且预后良好的卵巢癌病例。

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