Laframboise S, Dubuc-Lissoir J
Department of Obstetrics and Gynecology, Hôpital Notre-Dame, Université de Montréal, Quebec, Canada.
Gynecol Oncol. 1997 Feb;64(2):279-81. doi: 10.1006/gyno.1996.4562.
In mature women, the most common histological cell type of ovarian cancer is of epithelial origin. In children and adolescents, germ cell tumors are the most frequent. We report a case of a serous papillary cystadenocarcinoma FIGO stage IIIC in a 19-year-old female. She presented with a 6-month history of vague lower abdominal pain. Preoperative CA-125 was elevated at 296 kU/liter. At laparotomy, she was found to have stage IIIC disease. A debulking procedure including total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and lymph node sampling was performed. The immediate postoperative course was complicated by fulminant disseminated intravascular coagulopathy. She was subsequently treated with six courses of cyclophosphamide and carboplatin. Twenty-four months after surgery, the patient has no evidence of disease despite an increased CA-125 of 51 kU/liter.
在成年女性中，卵巢癌最常见的组织学细胞类型是上皮起源。在儿童和青少年中，生殖细胞肿瘤最为常见。我们报告一例19岁女性的浆液性乳头状囊腺癌，国际妇产科联盟（FIGO）分期为IIIC期。她有6个月的下腹部隐痛病史。术前CA-125升高至296 kU/升。剖腹手术时，发现她患有IIIC期疾病。进行了减瘤手术，包括全腹子宫切除术、双侧输卵管卵巢切除术、大网膜切除术和淋巴结取样。术后即刻病程因暴发性弥散性血管内凝血而复杂化。随后她接受了六个疗程的环磷酰胺和卡铂治疗。手术后24个月，尽管CA-125升高至51 kU/升，但患者无疾病证据。
