Moen M D, Cliby W A, Wilson T O
Department of Obstetrics and Gynecology, Mayo Clinic and Foundation, Rochester, Minnesota 55905.
Gynecol Oncol. 1994 May;53(2):274-6. doi: 10.1006/gyno.1994.1130.
Epithelial ovarian cancer is the most common cause of death due to gynecologic malignancies in adults, but is rare in children and adolescents. The majority of ovarian cancers in children and adolescents are stage I at diagnosis and conservative management with preservation of fertility is often possible. Twenty-nine serous epithelial cancers have been reported in females under age 20, only two of which are known to be advanced stage (both stage III). We present a case of advanced stage papillary serous cystadenocarcinoma in a 15-year-old female treated with bilateral salpingo-oophorectomy and debulking surgery followed by combination chemotherapy.
上皮性卵巢癌是成人妇科恶性肿瘤最常见的死亡原因，但在儿童和青少年中罕见。儿童和青少年的大多数卵巢癌在诊断时为I期，通常可以进行保留生育功能的保守治疗。据报道，20岁以下女性中有29例浆液性上皮癌，其中只有2例已知为晚期（均为III期）。我们报告一例15岁女性晚期乳头状浆液性囊腺癌病例，该患者接受了双侧输卵管卵巢切除术和肿瘤减灭术，随后进行联合化疗。
