Gupta M A, Schork N J, Ellis C N
Department of Psychiatry, University of Michigan Medical School, Ann Arbor.
J Am Acad Dermatol. 1994 Jun;30(6):969-72. doi: 10.1016/s0190-9622(94)70119-9.
The psychosocial aspects of the treatment of photodamaged skin have received little attention.
We prospectively examined the psychosocial correlates of the treatment of mildly to severely photodamaged skin.
Sixty subjects (age, 53.3 +/- 1.3 years [mean +/- standard error]; 35 receiving retinoic acid and 25 the inactive vehicle) completed a battery of psychosocial ratings before starting therapy and after 24 weeks of therapy with retinoic acid or vehicle.
Before therapy, the subjects had pathologically high obsessive-compulsiveness scores (measured by the Brief Symptom Inventory [BSI]). From before to after therapy, the retinoic acid group reported decreased obsessive-compulsiveness (BSI) (p = 0.01), and decreased phobic anxiety (BSI) (p = 0.04), whereas the vehicle group reported an increase (p < 0.05) in both these symptom dimensions.
High obsessive-compulsiveness (BSI), which is associated with excessive perfectionism and need for control, probably predisposed the subjects to seek treatment of their wrinkles. In the retinoic acid group but not the vehicle group there was an improvement in obsessive-compulsiveness and decreased anxiety in previously anxiety-provoking situations.
光损伤皮肤治疗的社会心理方面很少受到关注。
我们前瞻性地研究了轻度至重度光损伤皮肤治疗的社会心理相关因素。
60名受试者（年龄53.3±1.3岁[均值±标准误]；35名接受维甲酸治疗，25名接受无活性赋形剂治疗）在开始治疗前以及接受维甲酸或赋形剂治疗24周后完成了一系列社会心理评分。
治疗前，受试者的强迫症状评分（通过简明症状量表[BSI]测量）在病理上偏高。从治疗前到治疗后，维甲酸组报告强迫症状（BSI）减轻（p = 0.01），恐惧焦虑（BSI）减轻（p = 0.04），而赋形剂组报告这两个症状维度均增加（p < 0.05）。
与过度完美主义和控制需求相关的高强迫症状（BSI）可能使受试者倾向于寻求皱纹治疗。在维甲酸组而非赋形剂组中，强迫症状有所改善，并且在先前引发焦虑的情况下焦虑减轻。
