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[含庆大霉素气雾剂制剂(庆大霉素气雾剂)的实验研究]

[Experimental study of an aerosol preparation containing gentamicin (gentasol)].

作者信息

Rubtsova L K, Musiĭchenko A N, Eĭdel'shteĭn S I

出版信息

Antibiotiki. 1976 Feb;21(2):166-9.

PMID:818945
Abstract

Composition of a suspension aerosol drug, gentasol for local application was developed. It contained gentamycin and prednisolon. The antimicrobial properties of the drug were studied in vitro. It was found that gentasol had a pronounced antimicrobiol effect and inhibited the growth of many microorganisms including cultures resistant to other antibiotics. The drug was active against Ps. aeruginosa and Proteus, which is an advantage of it as compared to other antibiotic aerosol drugs. The study showed that gentasol had self-sterilizing properties.

摘要

开发了一种用于局部应用的悬浮气雾剂药物——庆大松,其含有庆大霉素和泼尼松龙。对该药物的抗菌特性进行了体外研究。发现庆大松具有显著的抗菌作用,能抑制包括对其他抗生素耐药的培养物在内的多种微生物的生长。该药物对铜绿假单胞菌和变形杆菌有活性,与其他抗生素气雾剂药物相比,这是它的一个优势。研究表明庆大松具有自消毒特性。

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