Yu V Y, Rolfe P
Arch Dis Child. 1976 Apr;51(4):310-3. doi: 10.1136/adc.51.4.310.
Measurements of ventilation and respiratory mechanics were made before and after tube feeding in 24 infants. In 12 infants with the respiratory distresssyndrome tidal volume tended to fall after feeding; as the respiratory rate increased after feeding; as the respiratory rate increased after feeding, minute ventilation remained unchanged. Hypoventilation is therefore unlikely to be the cause of hypoxaemia after feeding. Compliance, resistance, and the work of breathing showed no changes after feeding. In 12 healthy infants feeding had no effects on pulmonary function. There was a slight rise in compliance and a tendency for work of breathing to fall after feeding. Respiratory rate, tidal volume, and minute ventilation remained unchanged. There was therefore no evidence of adverse effects of feeding on any of the factors measured. It is suggested that hypoxaemia without hypoventilation after feeding in infants with pre-existing respiratory distress syndrome might be attributable to a reduction in functional residual capacity associated with a greater extent of airways closure than before feeding.
对24名婴儿在管饲前后进行了通气和呼吸力学测量。在12名患有呼吸窘迫综合征的婴儿中，喂食后潮气量往往下降；喂食后呼吸频率增加；由于喂食后呼吸频率增加，分钟通气量保持不变。因此，低通气不太可能是喂食后低氧血症的原因。顺应性、阻力和呼吸功在喂食后无变化。在12名健康婴儿中，喂食对肺功能无影响。喂食后顺应性略有上升，呼吸功有下降趋势。呼吸频率、潮气量和分钟通气量保持不变。因此，没有证据表明喂食对所测量的任何因素有不良影响。有人提出，患有先前存在的呼吸窘迫综合征的婴儿喂食后无低通气的低氧血症可能归因于功能残气量的减少，这与喂食前相比气道关闭程度更大有关。
