Bucholc B, Banach W
Zakład Badania Surowic i Szczepionek PZH w Warszawie.
Med Dosw Mikrobiol. 1993;45(4):517-21.
The study was aimed at determination of concentration of total IgE and IgE specific for D. pteronyssinus in preparation IVIG Bioglobulin. Twelve series of Bioglobulin and 20 series (8 preparations) registered in Poland, were tested. It was found that all series of Bioglobulin contained IgE in amount from 34.5 iu/ml to 105 iu/ml. In only one series IgE specific against D. pteronyssinus was detected in amount of 0.93 j/ml. It is concluded that concentration of IgE in preparation Bioglobulin is comparable to amount of IgE in other IVIG preparations.
该研究旨在测定静脉注射免疫球蛋白制剂Bioglobulin中总IgE以及针对屋尘螨的特异性IgE的浓度。对12批Bioglobulin以及在波兰注册的20批(8种制剂)进行了检测。结果发现,所有批次的Bioglobulin中IgE含量在34.5 iu/ml至105 iu/ml之间。仅在一个批次中检测到针对屋尘螨的特异性IgE,含量为0.93 j/ml。结论是,Bioglobulin制剂中IgE的浓度与其他静脉注射免疫球蛋白制剂中的IgE含量相当。