Kellman R M, Huckins S C, King J, Humphrey D, Marentette L, Osborn D C
Department of Otolaryngology, SUNY Health Science Center, Syracuse 13210.
Laryngoscope. 1994 May;104(5 Pt 1):556-61. doi: 10.1002/lary.5541040509.
Rigid fixation using plates and screws is an accepted mode of repair for facial fractures and osteotomies. To avoid potential complications associated with metal implants, bioresorbable implants are being developed. A study was performed to assess the strength over time of three bioresorbable polymeric screws for facial bone reconstruction. Screws of each polymer type and a titanium control were implanted in the periorbital bones of eight rabbits. Rabbits were euthanized at various time intervals. Pull-out testing and histological analysis were performed. Results showed varying degrees of resorption and screw pull-out strength dependent on time and polymer type, and no change in the control. This study demonstrates that bioresorbable screws can be used in bone, although the optimal choices for human implantation are yet to be determined.
使用接骨板和螺钉进行坚固内固定是面部骨折和截骨术公认的修复方式。为避免与金属植入物相关的潜在并发症，可吸收植入物正在研发中。开展了一项研究以评估三种用于面部骨重建的可吸收聚合物螺钉随时间推移的强度。将每种聚合物类型的螺钉和一个钛质对照物植入八只兔子的眶周骨中。在不同时间间隔对兔子实施安乐死。进行拔出试验和组织学分析。结果显示，取决于时间和聚合物类型，螺钉出现不同程度的吸收和拔出强度变化，而对照物未发生变化。这项研究表明，可吸收螺钉可用于骨组织，尽管用于人体植入的最佳选择尚未确定。
