Ovsiannikov V I
Biull Eksp Biol Med. 1975 Jul;80(7):52-4.
Experiments were performed on the isolated cat hearts, coronary vessels being perfused with donor cat blood. Dihydroergotoxin injected into the coronary vessels (0.5 mg) decreased their vascular capacity. This resulted from active constriction of the coronary vessels, since it was seen in experiments with the heart arrested with strophathin as well. Active constriction of the coronary veins under the action of dihydroergotoxin was not related to its specific properties as an alpha-blocking drug, and resulted from a direct action of the drug on the smooth muscle of the coronary veins.
实验在离体猫心上进行，冠状动脉用供体猫血灌注。向冠状动脉内注射双氢麦角毒碱（0.5毫克）可降低其血管容量。这是由于冠状动脉的主动收缩所致，因为在使用毒毛花苷使心脏停搏的实验中也观察到了这种情况。双氢麦角毒碱作用下冠状动脉的主动收缩与其作为α受体阻断药的特性无关，而是该药物对冠状静脉平滑肌的直接作用所致。
