Savitz D A, Brett K M, Evans L E, Bowes W
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599.
Am J Epidemiol. 1994 Jun 1;139(11):1100-6. doi: 10.1093/oxfordjournals.aje.a116953.
The authors attempted to identify all medically treated miscarriages in Alamance County, North Carolina, between September 1988 and August 1991. Clinical and demographic characteristics of the cases were evaluated, and risks were calculated in relation to total pregnancies, including induced abortions. Miscarriage cases usually had positive pregnancy tests, and a sizable proportion (66% of whites, 72% of blacks) had a pathology report indicating the presence of a conceptus. Nineteen percent of the cases were identified in hospitals, a more common source for women who were unmarried, young, of low education, and had pregnancies of advanced gestational age. The risk of medically treated miscarriage was 7.7% among whites and 5.5% among blacks, with higher risks among older women. The lower risk among blacks, especially those with lower levels of education, suggests underascertainment, possibly resulting from a failure to seek treatment.
作者试图识别1988年9月至1991年8月期间北卡罗来纳州阿拉曼斯县所有接受药物治疗的流产病例。对这些病例的临床和人口统计学特征进行了评估,并计算了与包括人工流产在内的总妊娠相关的风险。流产病例通常妊娠试验呈阳性,相当一部分(66%的白人、72%的黑人)有病理报告表明存在孕体。19%的病例在医院被识别出来,对于未婚、年轻、教育程度低且妊娠孕周较大的女性来说,医院是更常见的识别来源。白人中接受药物治疗流产的风险为7.7%,黑人中为5.5%,年龄较大的女性风险更高。黑人中风险较低,尤其是教育程度较低的黑人,这表明存在漏报情况,可能是由于未能寻求治疗所致。