Ali A, Ashford R W
Institute of Pathobiology, Addis Ababa University, Ethiopia.
Ann Trop Med Parasitol. 1994 Feb;88(1):43-7. doi: 10.1080/00034983.1994.11812833.
A serological study of visceral leishmaniasis was carried out in a cohort of people in an endemic area of Ethiopia. The people were tested three times, at 6-monthly intervals. Seroprevalence at the start was 112 per 1000, and the annual rate of conversion from negative to positive was estimated as 106 per 1000. Both seroprevalence and incidence of seroconversion increased with age, and males showed higher rates than females, with a male:female ratio of seroconversion of 2:1. Accumulation of 6-monthly seroconversion rates was considered to give a better estimate of the annual rate itself, as the half-life of positive serology was only around 3 months.
在埃塞俄比亚一个流行地区的人群队列中开展了一项内脏利什曼病血清学研究。对这些人每隔6个月进行了3次检测。开始时的血清阳性率为每1000人中有112例，从阴性转为阳性的年转化率估计为每1000人中有106例。血清阳性率和血清学转换发生率均随年龄增加，男性的发生率高于女性，血清学转换的男女比例为2:1。由于阳性血清学的半衰期仅约3个月，因此将6个月的血清学转换率累积起来被认为能更好地估计年发生率本身。
