Warner J O, Price J F, Soothill J F, Hey E N
Lancet. 1978 Oct 28;2(8096):912-5. doi: 10.1016/s0140-6736(78)91630-6.
Hyposensitisation with Dermatophagoides pteronyssinus tyrosine absorbate in asthmatic children with bronchial sensitivity to D. pteronyssinus was effective in a 12-month double-blind controlled clinical trial. Compared with controls, treated children used a smaller quantity of drugs while maintaining clinical and lung function improvements. In most children who improved there was no change in immediate response to D. pteronyssinus on bronchial provocation test, but the late reaction was lost in half the patients and these showed the greatest improvement in symptoms.
在一项为期12个月的双盲对照临床试验中，对支气管对屋尘螨敏感的哮喘儿童使用屋尘螨酪氨酸吸附物进行减敏治疗是有效的。与对照组相比，接受治疗的儿童在维持临床症状改善和肺功能改善的同时，使用的药物量更少。在大多数病情好转的儿童中，支气管激发试验中对屋尘螨的即时反应没有变化，但一半的患者失去了迟发反应，这些患者的症状改善最为明显。
