Buck B E, Malinin T I
Department of Orthopaedics and Rehabilitation, University of Miami School of Medicine, FL 33101.
Clin Orthop Relat Res. 1994 Jun(303):8-17.
Currently, modern tissue banks routinely supply requested bone and soft-tissue allografts. These allografts are safe if tissue-bank personnel adhere to the existing methodology for excluding any donors with potential for disease transmission. The authors' discard rate after excision of tissues has been approximately 18%, reflecting their concern for allograft safety. The preparation of significant numbers of allografts is labor intensive and very expensive, as is multiphasic screening of donors. However, long-term success with a large number of bone or soft-tissue recipient patients has led physicians and patients to have confidence in the safety of allografts prepared as described.
目前，现代组织库通常会提供所需的骨和软组织同种异体移植物。如果组织库工作人员遵循现有的方法来排除任何有疾病传播风险的捐赠者，这些同种异体移植物是安全的。作者切除组织后的丢弃率约为18%，这反映了他们对同种异体移植物安全性的关注。制备大量的同种异体移植物需要耗费大量人力且成本很高，对捐赠者进行多阶段筛查也是如此。然而，大量骨或软组织接受患者的长期成功治疗使医生和患者对按上述方法制备的同种异体移植物的安全性充满信心。
