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艾滋病患者血液培养检测分枝杆菌的结果。

Results of blood cultures for detection of mycobacteria in AIDS patients.

作者信息

Truffot-Pernot C, Lecoeur H F, Maury L, Dautzenberg B, Grosset J

机构信息

Laboratoire Central de Bactériologie, Clinique de Physiopathologie Respiratoire, Groupe Hospitalier Pitié-Salpêtrière, Paris.

出版信息

Tubercle. 1989 Sep;70(3):187-91. doi: 10.1016/0041-3879(89)90049-4.

DOI:10.1016/0041-3879(89)90049-4
PMID:2694553
Abstract

Since the advent of the acquired immunodeficiency syndrome (AIDS) numerous M. avium intracellulare disseminated infections have been recognised. Blood culture is a convenient method for diagnosing these infections. At Pitié-Salpêtrière hospital AIDS patients with persistent unexplained fever each had three blood cultures. The blood samples, taken on 3 consecutive days without taking in account fever peaks, were collected in the Isolator-10 lysis-centrifugation system and inoculated onto Löwenstein-Jensen medium with and without 0.25% sodium pyruvate. From February 1986-September 1987, 564 samples taken from 165 patients were cultivated for the detection of mycobacteria. Sixty one (10.8%) taken from 19 patients (11.5%) were positive. M. avium intracellulare was the most frequently isolated mycobacterial species. In 10 patients, the positive blood culture was the only or the first positive culture for mycobacteria.

摘要

自获得性免疫缺陷综合征(艾滋病)出现以来,已认识到许多鸟分枝杆菌胞内菌播散性感染。血培养是诊断这些感染的便捷方法。在皮蒂 - 萨尔佩特里埃医院,患有持续性不明原因发热的艾滋病患者每人进行三次血培养。血样在连续3天采集,不考虑发热高峰,收集于Isolator - 10裂解离心系统中,并接种到含和不含0.25%丙酮酸钠的罗 - 琴培养基上。从1986年2月至1987年9月,对165例患者采集的564份样本进行培养以检测分枝杆菌。从19例患者(11.5%)采集的61份样本(10.8%)呈阳性。鸟分枝杆菌胞内菌是最常分离出的分枝杆菌菌种。在10例患者中,阳性血培养是分枝杆菌的唯一或首个阳性培养结果。

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Results of blood cultures for detection of mycobacteria in AIDS patients.艾滋病患者血液培养检测分枝杆菌的结果。
Tubercle. 1989 Sep;70(3):187-91. doi: 10.1016/0041-3879(89)90049-4.
2
Recovery of mycobacteria from blood in mycobacteria growth indicator tube and Lowenstein-Jensen slant after lysis-centrifugation.经裂解离心后,在分枝杆菌生长指示管和罗-琴斜面培养基中从血液中分离出分枝杆菌。
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[Disseminated mycobacterial infections in patients with HIV/AIDS. Evaluation of blood cultures].[艾滋病病毒/艾滋病患者的播散性分枝杆菌感染。血培养评估]
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Broth culture: the modern 'guinea-pig' for isolation of mycobacteria.肉汤培养:用于分离分枝杆菌的现代“实验动物”。
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Bacteremia due to Mycobacterium avium-intracellulare in the acquired immunodeficiency syndrome.获得性免疫缺陷综合征中鸟分枝杆菌-胞内分枝杆菌所致的菌血症
Ann Intern Med. 1983 Dec;99(6):782-5. doi: 10.7326/0003-4819-99-6-782.

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Bull World Health Organ. 1997;75(4):361-6.
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Formulation and efficacy of liposome-encapsulated antibiotics for therapy of intracellular Mycobacterium avium infection.脂质体包裹抗生素治疗细胞内鸟分枝杆菌感染的制剂与疗效
Antimicrob Agents Chemother. 1995 Sep;39(9):2104-11. doi: 10.1128/AAC.39.9.2104.
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Utility of paired blood cultures and smears in diagnosis of disseminated Mycobacterium avium complex infections in AIDS patients.配对血培养和涂片在艾滋病患者播散性鸟分枝杆菌复合群感染诊断中的应用
J Clin Microbiol. 1994 Mar;32(3):841-2. doi: 10.1128/jcm.32.3.841-842.1994.
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Characterization of a Mycobacterium tuberculosis insertion sequence, IS6110, and its application in diagnosis.结核分枝杆菌插入序列IS6110的特性及其在诊断中的应用。
J Clin Microbiol. 1990 Dec;28(12):2668-73. doi: 10.1128/jcm.28.12.2668-2673.1990.