Manning D D, Manning J K, Reed N D
J Exp Med. 1976 Jul 1;144(1):288-92. doi: 10.1084/jem.144.1.288.
Neonatally initiated injection of anti-mu antiserum in mice has been shown to suppress the formation of reaginic antibodies in response to infection with the intestinal nematode, Nippostrongylus brasiliensis. This observation supports the hypothesis that IgE-producing cells arise from IgM-bearing precursors.
已表明,在新生小鼠中注射抗μ抗血清可抑制其针对巴西日圆线虫肠道感染产生反应性抗体的形成。这一观察结果支持了产生IgE的细胞源自带有IgM的前体细胞这一假说。