Brower K J, Mudd S, Blow F C, Young J P, Hill E M
Alcohol Research Center, University of Michigan Medical School, Ann Arbor.
Alcohol Clin Exp Res. 1994 Feb;18(1):196-201. doi: 10.1111/j.1530-0277.1994.tb00903.x.
We conducted a retrospective chart review of older (n = 48; mean age = 69) and younger (n = 36; mean age = 30) patients who were admitted to residential/inpatient treatment for alcohol withdrawal and dependence. Although the two age groups did not differ in terms of recent drinking history, the elderly group had significantly more withdrawal symptoms for a longer duration than the younger group. The elderly group also had more symptoms of cognitive impairment, daytime sleepiness, weakness, and high blood pressure. Finally, no significant differences were found between age groups in either the dosage or number of days of detoxification medication, although a trend was found for more days of medication in the elderly. We conclude that alcohol withdrawal may be more severe in elderly than in younger persons. Accordingly, treatment may take longer and should target the specific profile of symptoms that characterize alcohol withdrawal in the elderly.
我们对因酒精戒断和依赖而入住住院/住院治疗的老年患者（n = 48；平均年龄 = 69岁）和年轻患者（n = 36；平均年龄 = 30岁）进行了回顾性病历审查。尽管两个年龄组在近期饮酒史方面没有差异，但老年组的戒断症状明显更多，且持续时间比年轻组长。老年组还存在更多认知障碍、日间嗜睡、虚弱和高血压症状。最后，在解毒药物的剂量或使用天数方面，年龄组之间未发现显著差异，尽管发现老年患者使用药物的天数有增加趋势。我们得出结论，老年患者的酒精戒断可能比年轻患者更严重。因此，治疗可能需要更长时间，并应针对老年患者酒精戒断所特有的症状特征。
