García Paez J M, Carrera San Martín A, Jorge-Herrero E, Millán I, Navidad R, Candela I, García Sestafe J V, Castillo-Olivares J L
Service of Experimental Surgery, Clínica Puerta de Hierro, Madrid, Spain.
Biomaterials. 1994 Feb;15(3):172-6. doi: 10.1016/0142-9612(94)90063-9.
Our study of the different biomaterials used in the construction of biological cardiac prostheses has shown it to be of vital importance that the physical properties of the tissue and of the suture that anchors it to the rigid polymeric support are compatible. By means of dynamic tests, we have determined the fatigue curve in sutured bovine pericardial tissue, expressed by the equation log y = 1.27 +/- 0.18 (0.26 +/- 0.05) log t, where y is the initial fatigue stress (MPa) and t is the time (min) it takes to achieve permanent deformation of the tissue. By applying this correction, we determine a set of values for stress-time which, when compared with those obtained with a non-sutured sample, reveal a significant fall in this ratio and, thus, a decrease in the durability. The use of suture threads of lesser elasticity than the pericardium may play an important role in reducing the durability of the bioprosthesis constructed with these materials.
我们对用于构建生物心脏假体的不同生物材料的研究表明，组织的物理特性以及将其固定到刚性聚合物支架上的缝线的物理特性相互兼容至关重要。通过动态测试，我们确定了缝合牛心包组织中的疲劳曲线，其由方程log y = 1.27 +/- 0.18 (0.26 +/- 0.05) log t表示，其中y是初始疲劳应力（MPa），t是组织达到永久变形所需的时间（分钟）。通过应用此校正，我们确定了一组应力 - 时间值，与未缝合样本获得的值相比，该比率显著下降，从而耐久性降低。使用弹性比心包小的缝线可能在降低用这些材料构建的生物假体的耐久性方面起重要作用。
