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p53 immunohistochemistry: a word of caution.

作者信息

Battifora H

出版信息

Hum Pathol. 1994 May;25(5):435-7. doi: 10.1016/0046-8177(94)90113-9.

DOI:10.1016/0046-8177(94)90113-9
PMID:8200635
Abstract
摘要

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p53 immunohistochemistry: a word of caution.
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Mutational spectra and immunohistochemical analyses of p53 in human cancers.人类癌症中p53的突变谱及免疫组化分析。
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p53 protein detected by immunohistochemical staining is not always mutant.
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p53 in tumour pathology: can we trust immunohistochemistry?--Revisited!肿瘤病理学中的p53:我们能信赖免疫组织化学吗?——再探讨!
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Prognostic significance of p53 overexpression and mutation in colorectal adenocarcinomas.p53过表达和突变在结直肠癌中的预后意义
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Negative immunohistochemical staining of p53 protein does not always reflect wild-type p53 gene in cancer cells.p53蛋白的免疫组化染色阴性并不总是反映癌细胞中的野生型p53基因。
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Immunoreactivity for p53 and mdm2 and the detection of p53 mutations in human malignant mesothelioma.人恶性间皮瘤中p53和mdm2的免疫反应性及p53突变的检测
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