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[通过放射免疫扩散和血凝抑制反应评估流感疫苗接种后的抗体水平]

[Evaluation of the postvaccination level of influenza antibodies by means of the radial immunodiffusion and hemagglutination inhibition reactions].

作者信息

Vavilova Iu G, Gorev N E, Zykov M P

出版信息

Vopr Virusol. 1976 Mar-Apr(2):158-61.

PMID:820079
Abstract

Comparative data on the antibody levels obtained by the radial immunodiffusion and hemagglutination inhibition tests were studied. The possibility of using the radial immunodiffusion test for evaluation of the level of influenza antibody in human sera was confirmed. Because this method has comparatively low sensitivity (positive results were obtained only with sera having angihemagglutinin titers of 1:80 or higher), it may have only a limited use in studies of immunogenic activity of live influenza vaccines.

摘要

对通过放射免疫扩散和血凝抑制试验获得的抗体水平的比较数据进行了研究。证实了使用放射免疫扩散试验评估人血清中流感抗体水平的可能性。由于该方法的灵敏度相对较低(仅在血管血凝素滴度为1:80或更高的血清中获得阳性结果),因此在活流感疫苗免疫原活性研究中的应用可能有限。

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