Hodges J R
University of Cambridge Neurology Unit, Addenbrooke's Hospital, UK.
J Neurol Neurosurg Psychiatry. 1994 May;57(5):605-8. doi: 10.1136/jnnp.57.5.605.
To assess semantic memory and frontal executive function, two patients underwent neuropsychological testing during transient global amnesia (TGA) and after an interval of 6-8 weeks. In spite of a profound deficit in anterograde verbal and non-verbal memory, semantic memory was normal, as judged by category fluency measures, picture naming, and picture-word and picture-picture matching, and reading ability was normal. Similarly, there were no deficits on a number of tests known to be sensitive to frontal executive dysfunction. A hexamethylpropyleneamine-oxime (HMPAO) single photon emission CT (SPECT) scan, obtained on one patient 24 hours post-TGA, showed focal left temporal lobe hypoperfusion which had resolved three months later. The observed dissociation between episodic and semantic memory is discussed in the light of contemporary cognitive theories of memory organisation.
为评估语义记忆和额叶执行功能，两名患者在短暂性全面遗忘症（TGA）期间及6 - 8周后接受了神经心理学测试。尽管顺行性言语和非言语记忆存在严重缺陷，但通过类别流畅性测量、图片命名、图片 - 单词及图片 - 图片匹配判断，语义记忆正常，阅读能力也正常。同样，在多项已知对额叶执行功能障碍敏感的测试中也未发现缺陷。一名患者在TGA后24小时进行的六甲基丙烯胺肟（HMPAO）单光子发射计算机断层扫描（SPECT）显示左颞叶局灶性灌注不足，三个月后已恢复。根据当代记忆组织认知理论对观察到的情景记忆和语义记忆分离现象进行了讨论。
