短暂性全面性遗忘症中的情景记忆：编码、存储还是检索缺陷？
Episodic memory in transient global amnesia: encoding, storage, or retrieval deficit?
作者信息
Eustache F, Desgranges B, Laville P, Guillery B, Lalevée C, Schaeffer S, de la Sayette V, Iglesias S, Baron J C, Viader F
机构信息
INSERM U320 and Services de Neurologie, CHU Côte de Nane, Caen, France.
出版信息
J Neurol Neurosurg Psychiatry. 1999 Feb;66(2):148-54. doi: 10.1136/jnnp.66.2.148.
OBJECTIVES
To assess episodic memory (especially anterograde amnesia) during the acute phase of transient global amnesia to differentiate an encoding, a storage, or a retrieval deficit.
METHODS
In three patients, whose amnestic episode fulfilled all current criteria for transient global amnesia, a neuropsychological protocol was administered which included a word learning task derived from the Grober and Buschke's procedure.
RESULTS
In one patient, the results suggested an encoding deficit, and in two others, a storage deficit.
CONCLUSIONS
The encoding/storage impairment concerning anterograde amnesia documented in our patients stands in clear contrast with the impairment in retrieval which must underly the retrograde amnesia that also characterises transient global amnesia. This dissociation in turn favours the idea of a functional independence among the cognitive mechanisms that subserve episodic memory.
目的
评估短暂性全面性遗忘急性期的情景记忆（尤其是顺行性遗忘），以区分编码、存储或检索缺陷。
方法
对三名遗忘发作符合当前短暂性全面性遗忘所有标准的患者实施了一项神经心理学方案，其中包括一项源自格罗伯和布施克程序的单词学习任务。
结果
一名患者的结果提示存在编码缺陷，另外两名患者提示存在存储缺陷。
结论
我们的患者中记录到的与顺行性遗忘相关的编码/存储损害，与检索损害形成鲜明对比，而检索损害必定是短暂性全面性遗忘所具有的逆行性遗忘的基础。这种分离反过来支持了服务于情景记忆的认知机制之间功能独立的观点。
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