Tao T W, Floersheim G L
Acta Haematol. 1976;55(6):332-7. doi: 10.1159/000208037.
Lethally irradiated mice were reconstituted with bone marrow cells from 'nude' or normal mice. It was found that the radioprotective capacity of bone marrow cells from normal and thymusless 'nude' mice is similar and that the immune responses to sheep red cells in radiation chimeras reconstituted with normal and nude bone marrow cells are also similar. Bone marrow cells from nude mice, in spite of the lack of the thymus, develop into hematopoietic cells and contain also T-precursor cells.
对受到致死剂量照射的小鼠,用来自“裸”鼠或正常小鼠的骨髓细胞进行重建。结果发现,正常小鼠和无胸腺“裸”鼠的骨髓细胞的辐射防护能力相似,并且用正常和裸鼠骨髓细胞重建的辐射嵌合体对绵羊红细胞的免疫反应也相似。尽管缺乏胸腺,裸鼠的骨髓细胞仍能发育成造血细胞,并且还含有T前体细胞。