Todriia T V
Biull Eksp Biol Med. 1992 Jul;114(8):206-8.
Radioprotective capacity of bone marrow CFUs of adult thymectomized mice was studied. Lethally irradiated mice were inoculated with bone marrow of mice thymectomized 8-11 months before. The colony forming capacity and proliferative rate of CFUs were studied 1-7.5 months after obtaining the radiation chimeras. It has been shown that proliferative capacity of bone marrow of adult thymectomized mice was reduced in comparison with that of normal animals. It is related to the decrease (4-fold) of the proliferative rate of bone marrow of thymectomized mice which was inoculated into lethally irradiated recipients 1 month before. We also found that the content of CFUs in bone of those chimeras was reduced later--after 7.5 months. In this period (1-7.5 months) the cellularity of bone marrow did not change.
研究了成年去胸腺小鼠骨髓集落形成单位（CFUs）的辐射防护能力。对接受致死剂量照射的小鼠接种8 - 11个月前已去胸腺的小鼠的骨髓。在获得辐射嵌合体后1 - 7.5个月，研究CFUs的集落形成能力和增殖率。结果表明，与正常动物相比，成年去胸腺小鼠骨髓的增殖能力降低。这与1个月前接种到接受致死剂量照射受体体内的去胸腺小鼠骨髓增殖率下降（4倍）有关。我们还发现，这些嵌合体骨髓中CFUs的含量在7.5个月后降低。在此期间（1 - 7.5个月），骨髓细胞数量没有变化。
