MMWR Recomm Rep. 1994 May 13;43(RR-7):1-7.
This report provides interim biosafety guidelines for preventing laboratory-associated infections with agents that cause hantavirus pulmonary syndrome. The guidelines are based on extensive laboratory experience with the other hantaviruses--particularly work involving the use of permissive host animal species--and on the limited experience with a hantavirus recently isolated from deer mice. The guidelines address handling patient-derived specimens, propagating viruses in culture (including viral concentrate preparations), and housing and handling infected animals. These recommendations were developed with the assistance of expert consultants during a meeting of the American Society of Tropical Medicine and Hygiene, Subcommittee on Arbovirus Laboratory Safety, November 2, 1993, in Atlanta.
本报告提供了临时生物安全指南，以预防因可导致汉坦病毒肺综合征的病原体引发的实验室相关感染。这些指南基于对其他汉坦病毒的广泛实验室经验——尤其是涉及使用易感宿主动物物种的工作——以及对最近从鹿鼠中分离出的一种汉坦病毒的有限经验。这些指南涉及处理患者来源的标本、在培养物中繁殖病毒（包括病毒浓缩液制备）以及饲养和处理感染动物。这些建议是在1993年11月2日于亚特兰大召开的美国热带医学和卫生学会虫媒病毒实验室安全小组委员会会议期间，在专家顾问的协助下制定的。
