Tjan-Heijnen V C, Harthoorn-Lasthuizen E J, Kurstjens R M, Koolen M I
Department of Internal Medicine, Bosch Medicentrum, Groot Ziekengasthuis, 's Hertogenbosch, Netherlands.
Neth J Med. 1994 Mar;44(3):91-4.
Patients with hypothyroidism often complain about easy bruising. We describe a patient with a postpartum acquired bleeding tendency. Hypothyroidism was suspected and confirmed biochemically. After substitution therapy with levothyroxine the bleeding tendency recovered completely. The coagulation disorder appeared to be based on an acquired von Willebrand's disease, secondary to the hypothyroidism. In patients with von Willebrand's disease underlying diseases have to be excluded.
甲状腺功能减退症患者常主诉容易出现瘀伤。我们描述了一名产后获得性出血倾向的患者。怀疑其患有甲状腺功能减退症,并通过生化检查得以确诊。使用左甲状腺素替代治疗后,出血倾向完全恢复。凝血障碍似乎是基于一种后天获得性血管性血友病,继发于甲状腺功能减退症。对于血管性血友病患者,必须排除潜在疾病。