Tabidze Z Sh
Ter Arkh. 1994;66(3):35-8.
Gastrofibroscopic findings for 164 patients with bacterial asthma (BA) showed high frequency of gastroduodenal ulcer occurrence. Mucosal biopsy extracts from the stomach and duodenum of BA patients demonstrate high hemocoagulative and low anticoagulative activities. Enhanced fibrin-formation in inhibition of fibrinolytic activity in gastroduodenal mucosa vessels causes local circulatory disorders. This fact explains well frequent findings of the ulcer in BA patients. Antibiotic therapy does not affect enzymatic activity of gastroduodenal zone in BA patients and eventually does not aggravate ulcer lesions. Corticosteroid hormones stimulate hemocoagulative activity in the zone and further inhibit anticoagulative activity. This results in further ulceration and appearance of new lesions.
对164例细菌性哮喘（BA）患者的胃纤维镜检查结果显示，胃十二指肠溃疡的发生率很高。BA患者胃和十二指肠的黏膜活检提取物显示出高凝血活性和低抗凝活性。胃十二指肠黏膜血管中纤维蛋白形成增强，纤溶活性受到抑制，从而导致局部循环障碍。这一事实很好地解释了BA患者溃疡常见的原因。抗生素治疗对BA患者胃十二指肠区域的酶活性没有影响，最终也不会加重溃疡病变。皮质类固醇激素会刺激该区域的凝血活性，并进一步抑制抗凝活性。这会导致进一步溃疡形成和新病变出现。
