以恒河猴母婴分离作为人类抑郁症模型的研究：重新审视
Mother-infant separation in rhesus monkeys as a model of human depression. A reconsideration.
作者信息
Lewis J K, McKinney W T, Young L D, Kraemer G W
出版信息
Arch Gen Psychiatry. 1976 Jun;33(6):699-705. doi: 10.1001/archpsyc.1976.01770060035006.
Abstract
Nineteen rhesus monkeys between the ages of 5.9 and 8.5 months were separated from their mothers in five different studies. While in two of the studies, data indicated behavioral responses roughly parallel to Bowlby's protest-despair response to maternal separations, data across all five studies were sufficiently variable to bring this technique into serious question as a reliable and predictable animal model for neurobiologic and rehabilitative studies.
摘要
在五项不同的研究中，19只年龄在5.9至8.5个月之间的恒河猴与其母亲分离。在其中两项研究中，数据表明行为反应大致与鲍尔比针对母婴分离的抗议-绝望反应相似，但在所有五项研究中，数据的变化幅度都很大，以至于作为神经生物学和康复研究的可靠且可预测的动物模型，这种技术受到了严重质疑。
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