Blackbourne L H, Tribble C G, Langenburg S E, Mauney M C, Buchanan S A, Sinclair K N, Kron I L
Department of Surgery, University of Virginia Health Sciences Center, Charlottesville.
Ann Surg. 1994 Jun;219(6):693-6; discussion 696-8. doi: 10.1097/00000658-199406000-00013.
The authors ascertained the optimal timing of repair of an abdominal aortic aneurysm (AAA) after coronary artery revascularization.
Cardiac events are the most common cause of death after elective repair of AAA. Preoperative coronary revascularization has significantly reduced postoperative cardiac complications after elective AAA repair. Currently, most patients undergo repair of asymptomatic AAA within 6 months after the coronary revascularization.
The authors performed a retrospective review of patients who underwent repair or scheduled repair of an asymptomatic AAA within 6 months after coronary artery bypass graft (CABG) between March 1988 and October 1993.
There was no mortality in the group of patients (n = 14) who underwent repair of AAA simultaneously or within 14 days of coronary revascularization. In contrast, there was a significantly increased mortality rate of 3 of 9 (33%) in patients scheduled to undergo repair of the AAA more than 2 weeks after coronary revascularization (p < 0.05). All nonsurvivors died between 16 and 29 days after CABG, and died as a result of ruptured AAA.
Elective AAA repair should be undertaken simultaneously or within 2 weeks of coronary artery revascularization because of an increased risk of postoperative AAA rupture seen after this time period. In addition, simultaneous or early postoperative AAA repair does not increase the overall operative risk.
作者确定冠状动脉血运重建术后腹主动脉瘤(AAA)修复的最佳时机。
心脏事件是择期修复AAA后最常见的死亡原因。术前冠状动脉血运重建显著降低了择期AAA修复术后的心脏并发症。目前,大多数患者在冠状动脉血运重建后6个月内接受无症状AAA的修复。
作者对1988年3月至1993年10月期间在冠状动脉旁路移植术(CABG)后6个月内接受无症状AAA修复或计划修复的患者进行了回顾性研究。
在冠状动脉血运重建同时或14天内接受AAA修复的患者组(n = 14)中无死亡病例。相比之下,在冠状动脉血运重建2周后计划接受AAA修复的患者中,死亡率显著增加,9例中有3例(33%)死亡(p < 0.05)。所有非幸存者均在CABG后16至29天内死亡,死因是AAA破裂。
由于在此时间段后可见术后AAA破裂风险增加,择期AAA修复应在冠状动脉血运重建同时或2周内进行。此外,同时或术后早期AAA修复不会增加总体手术风险。