Fedotova E P, Shastina G V
Arkh Patol. 1994 Jan-Feb;56(1):61-5.
118 late abortions were investigated at week 18-28 of pregnancy with the use of light and immunofluorescent microscopy. Intrauterine infections were found in 86 cases including 44 observations of mycoplasmosis, 16-M. hominis, 18-M. pneumoniae, 10-U. urealyticum. Histologically similar changes were found in the form of vacuolar degeneration of the amnion, trophoblast of the basal lamina and foetal coats, inner foetal organs and neuroepithelial cells in the central nervous system. Apart from this, focal leucocytic-lymphocytic infiltration was observed. Marked myeloid hematopoiesis was found in the liver. Maximum changes were found in the placenta and foetal organs in chronic placental deficiency.
对118例妊娠18 - 28周的晚期流产病例进行了光镜和免疫荧光显微镜检查。发现86例存在宫内感染,其中支原体感染44例,人型支原体感染16例,肺炎支原体感染18例,解脲脲原体感染10例。组织学上可见羊膜、基底层滋养层、胎儿被膜、胎儿内部器官及中枢神经系统神经上皮细胞出现空泡变性。除此之外,还观察到局灶性白细胞 - 淋巴细胞浸润。肝脏中发现明显的髓系造血。慢性胎盘功能不全时,胎盘和胎儿器官的变化最为明显。