Kalashnikova E P, Tanakov A I, Zubzhitskaia L B, Bobkov V M
Arkh Patol. 1993;55(6):48-54.
96 placentas from mothers with genital mycoplasmosis diagnosed during the pregnancy (main group), and without mycoplasmosis (group for comparison) were studied. Histological study was performed in parallel with electron microscopy of the amnion and use of fluorescent antibodies. Progression of the involutive-degenerative changes in the placenta with the development of lipophanerosis and destruction of the extra-placental amnion epithelium were observed in the main group in parallel with the increase of the immunoglobulins studied (A, M, G), fibrinogen, C3-component of the complement with fixation of pathogenic immune complexes (IC). IC are observed in the placenta of 51 +/- 6.35% and in the extra-placental coats in 100% of mothers with mycoplasmosis versus 9 +/- 4.91% and 40%, respectively, in the comparison group. The presence of IC in the placenta and extra-placental coats correlates with the neurological symptoms in newborns and the increase of infectious-allergic diseases in children of the 1st year of life.
对96例孕期诊断为生殖道支原体感染的母亲的胎盘（主要组）以及未感染支原体的母亲的胎盘（对照组）进行了研究。组织学研究与羊膜电子显微镜检查及荧光抗体的使用同时进行。在主要组中，观察到随着所研究的免疫球蛋白（A、M、G）、纤维蛋白原、补体C3成分的增加以及致病性免疫复合物（IC）的固定，胎盘出现退行性变化并伴有脂褐素形成和胎盘外羊膜上皮破坏。支原体感染母亲中，51±6.35%的胎盘和100%的胎盘外膜出现IC，而对照组分别为9±4.91%和40%。胎盘和胎盘外膜中IC的存在与新生儿的神经症状以及1岁儿童感染性过敏性疾病的增加相关。
