Mondrup M, Anker N
Clin Chim Acta. 1976 Jun 15;69(3):463-9. doi: 10.1016/0009-8981(76)90120-0.
A specific and quantitative immunological method for determination of human erythrocyte carbonic anhydrase (HCA) isoenzyme B has been used to determine the contents of enzyme in the erythrocytes from healthy persons and from subjects with different types of anemia. The investigations have shown a statistically significant increase of HCA type B in the erythrocytes of subjects suffering from uremic anemia, cancer anemia, megaloblastic anemia while in sideropenic anemia the content was normal. In erythrocytes from patients with acute bleeding anemia the content of HCA type B was significantly decreased. An inverse relationship was found between B-hemoglobin and HCA type B in megaloblastic anemia but not in the other types of anemia.
一种用于测定人红细胞碳酸酐酶（HCA）同工酶B的特异性定量免疫方法，已被用于测定健康人和不同类型贫血患者红细胞中的酶含量。研究表明，尿毒症性贫血、癌症贫血、巨幼细胞贫血患者红细胞中B型HCA有统计学意义的增加，而缺铁性贫血患者的含量正常。急性出血性贫血患者红细胞中B型HCA的含量显著降低。在巨幼细胞贫血中发现B型血红蛋白与B型HCA呈负相关，但在其他类型贫血中未发现这种关系。
