Tsunemi K, Kanayama I, Kondo T, Tanigaki T, Ohta Y, Yanagimachi N
Department of Internal Medicine, Tokai University School of Medicine, Kanagawa.
Intern Med. 1993 Dec;32(12):891-4. doi: 10.2169/internalmedicine.32.891.
We describe two cases of acute eosinophilic pneumonia (AEP) presenting with high fever and hypoxia of acute onset with bilateral interstitial infiltrates on chest roentgenograms. Diagnosis was confirmed in each case by bronchoalveolar lavage and transbronchial lung biopsy in which the pathologic process was limited to the lung interstitium. High-resolution computed tomography (HRCT) of the thorax at the height of the disease process revealed peripheral ground-glass opacities along the bronchovascular bundles. Symptoms and radiologic abnormalities resolved spontaneously within two weeks. The HRCT-findings may reflect the pathologic process in AEP and the ground-glass opacities likely indicate spontaneous resolution without corticosteroid therapy.
我们描述了两例急性嗜酸性粒细胞性肺炎（AEP），均急性起病，表现为高热和缺氧，胸部X线片显示双侧间质性浸润。每例均通过支气管肺泡灌洗和经支气管肺活检确诊，病理过程局限于肺间质。在疾病高峰期进行的胸部高分辨率计算机断层扫描（HRCT）显示沿支气管血管束的外周磨玻璃样混浊。症状和影像学异常在两周内自发缓解。HRCT表现可能反映了AEP的病理过程，磨玻璃样混浊可能表明无需皮质类固醇治疗即可自发缓解。
