Maeno T, Maeno Y, Sando Y, Takahashi T, Yarita H, Tsukagoshi M, Suga T, Kurabayashi M, Nagai R
Second Department of Internal Medicine, Gunma University, Maebashi.
Intern Med. 2000 Feb;39(2):157-9. doi: 10.2169/internalmedicine.39.157.
In this case of acute eosinophilic pneumonia (AEP), eosinophils with hypersegmented nuclei emerged in the blood before the increase of eosinophil count. An 18-year-old woman complaining of fever, cough and dyspnea was admitted because of diffuse ground-glass opacities in her chest roentgenogram. On admission, her blood cell count revealed a marked increase of neutrophils. Although the number of eosinophils was normal, some of them contained three- or four-lobed nuclei. She was diagnosed to have AEP through bronchoalveolar lavage and transbronchial lung biopsy. The combination with acute clinical course, pulmonary infiltration and the presence of hypersegmented eosinophils in blood may imply the diagnosis of AEP.
在这例急性嗜酸性粒细胞性肺炎（AEP）中，在嗜酸性粒细胞计数增加之前，血液中就出现了核分叶过多的嗜酸性粒细胞。一名18岁女性因发热、咳嗽和呼吸困难就诊，胸部X线片显示弥漫性磨玻璃影而入院。入院时，她的血细胞计数显示中性粒细胞显著增多。虽然嗜酸性粒细胞数量正常，但其中一些含有三叶或四叶核。通过支气管肺泡灌洗和经支气管肺活检，她被诊断为AEP。急性临床病程、肺部浸润以及血液中存在核分叶过多的嗜酸性粒细胞相结合，可能提示AEP的诊断。
