Pettitt A R, Neoh C, Wong S H, Clark R E
Department of Haematology, Royal Liverpool University Hospital, UK.
Bone Marrow Transplant. 1994 Feb;13(2):225-7.
Vogt-Koyanagi-Harada (VKH) syndrome is an uncommon acute ophthalmological disorder, characterised by bilateral serous retinal detachment with diffuse choroiditis, in association with specific extra-ocular manifestations. We describe a patient with unequivocal VKH syndrome arising 49 days after matched unrelated donor bone marrow transplantation (BMT) performed as treatment for severe aplastic anaemia. The visual symptoms and retinal changes responded well to corticosteroids. The haematological relevance of VKH syndrome is to distinguish it from retinitis due to cytomegalovirus, which requires different therapy and has a far worse visual prognosis.
伏格特-小柳-原田（VKH）综合征是一种罕见的急性眼科疾病，其特征为双侧浆液性视网膜脱离伴弥漫性脉络膜炎，并伴有特定的眼外表现。我们描述了一名患有明确VKH综合征的患者，该综合征在作为严重再生障碍性贫血治疗进行的匹配无关供体骨髓移植（BMT）后49天出现。视觉症状和视网膜变化对皮质类固醇反应良好。VKH综合征在血液学方面的意义在于将其与巨细胞病毒引起的视网膜炎区分开来，后者需要不同的治疗方法且视觉预后要差得多。
