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伏格特-小柳-原田病:土耳其一家专业眼科医院患者的临床和人口统计学特征

Vogt-Koyanagi-Harada disease: clinical and demographic characteristics of patients in a specialized eye hospital in Turkey.

作者信息

Ozdal Pinar, Ozdamar Yasemin, Yazici Alper, Teke Mehmet Y, Ozturk Faruk

机构信息

Ulucanlar Eye Education and Training Hospital Ophthalmology Clinic , Ankara , Turkey and.

出版信息

Ocul Immunol Inflamm. 2014 Aug;22(4):277-86. doi: 10.3109/09273948.2013.856448. Epub 2013 Dec 11.

DOI:10.3109/09273948.2013.856448
PMID:24328424
Abstract

PURPOSE

To evaluate clinical and demographic features of Vogt-Kayanagi-Harada disease (VKH) disease in Turkish patients and compare them with previously published data.

METHODS

Demographic and clinical features of 32 patients diagnosed as VKH in a tertiary referral center were retrospectively reviewed.

RESULTS

The mean age at presentation was 33.6 ± 10.4 years. Seventy-five percent of the patients were female and 62.5% of the patients presented during the last 2 years. The disease was complete in 31.2%, incomplete in 50%, and probable in 18.8% of the patients. The clinical course was acute in 50%, chronic recurrent in 34.4%, and chronic in 15.6%. The most common findings were bilateral serous retinal detachment ± papillitis in acute cases and retinal pigment epithelial changes of the macula in chronic cases.

CONCLUSIONS

Although rare in Turkey, VKH disease seems to have increased during the last few years. The disease is incomplete and acute in half of the patients and has a quite good visual prognosis.

摘要

目的

评估土耳其患者伏格特-小柳-原田病(VKH)的临床和人口统计学特征,并与先前发表的数据进行比较。

方法

回顾性分析在一家三级转诊中心确诊为VKH的32例患者的人口统计学和临床特征。

结果

就诊时的平均年龄为33.6±10.4岁。75%的患者为女性,62.5%的患者在过去2年内发病。31.2%的患者病情为完全型,50%为不完全型,18.8%为疑似型。50%的患者临床病程为急性,34.4%为慢性复发型,15.6%为慢性型。最常见的表现为急性病例中的双侧浆液性视网膜脱离±视乳头炎,以及慢性病例中的黄斑区视网膜色素上皮改变。

结论

尽管在土耳其VKH病较为罕见,但在过去几年中似乎有所增加。半数患者病情为不完全型且呈急性,视觉预后相当良好。

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