Wolters U, Keller H W, Sorgatz S, Raab A, Pichlmaier H
Department of Surgery, University of Cologne, Germany.
Br J Surg. 1994 Apr;81(4):598-600. doi: 10.1002/bjs.1800810439.
Three different methods of preoperative bowel preparation were tested in a prospective randomized trial examining efficacy and morbidity. In all, 163 patients were treated by gut irrigation with Ringer's lactate, Prepacol or polyethylene glycol (PEG). Fluid retention, cleansing effect, postoperative complications and subjective acceptance were documented. Relevant weight gain and decrease in haematocrit indicating fluid retention were seen only after the use of Ringer's lactate. There were no significant differences in bowel cleansing. In the Prepacol group the postoperative complication rate was significantly increased. Prepacol was tolerated best, with few side-effects. PEG was better tolerated than Ringer's lactate, but vomiting occurred in 2 and 21 per cent of patients respectively. PEG is most suitable for bowel preparation in patients undergoing colorectal surgery.
在一项前瞻性随机试验中，对三种不同的术前肠道准备方法进行了测试，以检验其疗效和发病率。共有163例患者接受了乳酸林格液、Prepacol或聚乙二醇（PEG）肠道灌洗治疗。记录了液体潴留、清洁效果、术后并发症和主观接受度。仅在使用乳酸林格液后出现了提示液体潴留的相关体重增加和血细胞比容降低。肠道清洁方面无显著差异。Prepacol组术后并发症发生率显著增加。Prepacol耐受性最佳，副作用少。PEG的耐受性优于乳酸林格液，但分别有2%和21%的患者出现呕吐。PEG最适合结直肠手术患者的肠道准备。
