Fonzari M, Santoloci D, Farinini D
Divisione Neurologica, Ospedale S. Martino, Genova.
Clin Ter. 1994 Apr;144(4):329-32.
The efficacy of verapamil CR in migraine prophylaxis has been tested in an open study with 64 patients. The group of patients showed a significant decrease of the frequency, duration and severity score of their headache. All patients were treated for 3 months; thirty patients extended the treatment for 6 months without further improvement. In conclusion, verapamil CR is a useful drug with few side effects for migraine prophylaxis.
维拉帕米缓释片预防偏头痛的疗效已在一项有64名患者参与的开放性研究中得到检验。该组患者的头痛频率、持续时间和严重程度评分均显著降低。所有患者均接受了3个月的治疗;30名患者将治疗延长至6个月,但未取得进一步改善。总之,维拉帕米缓释片是一种预防偏头痛的有效药物,副作用较少。