Pedersen K N
Int J Oral Surg. 1976 Jun;5(3):133-41. doi: 10.1016/s0300-9785(76)80062-2.
Porous ceramic (Al2O3) implants with a pore size of 100--750 mum were used in the surgical treatment of four patients at the Department of Oral Surgery and Oral Medicine, Dental Faculty, University of Oslo. In two of the cases, ceramic implants were placed in small surgical defects in the edentulous maxillary alveolar ridge, while two patients were treated with mandibular ridge augmentation. All four individuals healed uneventfully, and the implants were firm and immovable 3 weeks postoperatively. No adverse tissue reactions were observed. Dentures were inserted over the implants 8 days to 6 weeks after implantation. In one of the cases, reoperation was performed because of 2 X 2 mm zone of exposure of the ceramic 4 weeks after denture insertion. Examination after observation times up to 15 months revealed clinically normal soft tissue over the implants. There were no complaints about wearing of the dentures. Radiographs at varying intervals after implantation did not disclose any pathologic changes or signs of resorption of bone adjacent to the ceramic implants.
孔径为100 - 750微米的多孔陶瓷（Al2O3）植入物被用于奥斯陆大学牙科学院口腔外科和口腔医学系对4例患者的外科治疗。其中2例，陶瓷植入物被放置在上颌无牙牙槽嵴的小手术缺损处，而另外2例患者接受了下颌牙槽嵴增高术。所有4例患者均顺利愈合，术后3周植入物稳固且不可移动。未观察到不良组织反应。在植入后8天至6周，在植入物上佩戴假牙。其中1例患者，在佩戴假牙4周后，因陶瓷有2×2毫米的暴露区域而进行了再次手术。观察长达15个月后的检查显示，植入物上方的软组织在临床上正常。患者对佩戴假牙没有任何抱怨。植入后不同时间间隔的X光片未显示陶瓷植入物邻近骨组织有任何病理变化或吸收迹象。
