Arrants J
Veterans Administration Hospital, Columbia, SC.
Heart Lung. 1994 Mar-Apr;23(2):118-22; 123-4.
Tissue insulin resistance and compensatory hyperinsulinemia cause early atherosclerosis and an increased cardiovascular risk for the non-insulin dependent diabetic individual. Evidence now indicates that a large and likely unrecognized number of individuals are insulin resistant and hyperinsulinemic and therefore share this risk. Ongoing investigation of this phenomenon may produce changes in the methods for earlier identification of these individuals and in the treatment of obesity, diabetes, and cardiovascular disease and may expand the areas in which nursing intervention can alter outcome.
组织胰岛素抵抗和代偿性高胰岛素血症会导致非胰岛素依赖型糖尿病个体早期发生动脉粥样硬化,并增加心血管疾病风险。目前有证据表明,大量可能未被认识到的个体存在胰岛素抵抗和高胰岛素血症,因此也面临这种风险。对这一现象的持续研究可能会改变早期识别这些个体的方法以及肥胖症、糖尿病和心血管疾病的治疗方法,并可能扩大护理干预能够改善预后的领域。