• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一枚炮弹造成的严重皮肤芥子气烧伤。

A serious skin sulfur mustard burn from an artillery shell.

作者信息

Ruhl C M, Park S J, Danisa O, Morgan R F, Papirmeister B, Sidell F R, Edlich R F, Anthony L S, Himel H N

机构信息

Department of Plastic Surgery, University of Virginia School of Medicine, Charlottesville 22908.

出版信息

J Emerg Med. 1994 Mar-Apr;12(2):159-66. doi: 10.1016/0736-4679(94)90693-9.

DOI:10.1016/0736-4679(94)90693-9
PMID:8207150
Abstract

Despite the Geneva Protocol of 1925 and the Paris Conference on Prohibition of Chemical Weapons in 1989, sulfur mustard and other chemical weapons continue to pose a hazard to both civilians and soldiers. The presence of artillery shells containing sulfur mustard, both in waters where these shells were dumped and in old battlefields, presents a problem in times of peace, especially for those who collect wartime memorabilia. Past literature has reported several hundred incidents involving fishermen who inadvertently pulled leaking shells aboard their fishing vessels, thereby exposing themselves to the vesicant chemical. Other literature reports exposure to children who found the chemical shells in old battlefields. The purpose of this article is to report the first case of a serious sulfur mustard burn that occurred after removing the detonator from an old artillery shell in a historic battle field near Verdun, France. The circumstances surrounding the injury, the diagnosis and management of injuries secondary to sulfur mustard, and the long-term consequences to the patient are presented and discussed. Although skin grafting has been used in the management of other chemical burn injuries, this report is the first to describe the need for split-thickness skin grafts in the management of a patient with sulfur mustard burns.

摘要

尽管有1925年的《日内瓦议定书》以及1989年的巴黎禁止化学武器会议,但芥子气和其他化学武器仍然对平民和士兵构成威胁。装有芥子气的炮弹存在于炮弹被倾倒的水域以及旧战场上,在和平时期造成了问题,尤其是对于那些收集战时纪念品的人来说。过去的文献报道了数百起事件,涉及渔民无意中将泄漏的炮弹拖上他们的渔船,从而使自己暴露于这种糜烂性化学物质中。其他文献报道了儿童在旧战场上发现化学炮弹而接触到这种物质的情况。本文的目的是报告第一例严重的芥子气烧伤病例,该病例发生在法国凡尔登附近的一个历史战场上,伤者从一枚旧炮弹上拆除雷管之后。文中介绍并讨论了受伤的相关情况、芥子气所致损伤的诊断和处理,以及对患者的长期影响。虽然皮肤移植已被用于其他化学烧伤的治疗,但本报告首次描述了在芥子气烧伤患者的治疗中需要使用中厚皮片移植。

相似文献

1
A serious skin sulfur mustard burn from an artillery shell.一枚炮弹造成的严重皮肤芥子气烧伤。
J Emerg Med. 1994 Mar-Apr;12(2):159-66. doi: 10.1016/0736-4679(94)90693-9.
2
Sulfur Mustard Exposure from Dredged Artillery Shell in a Commercial Clammer.一名商业捕蛤者因疏浚的炮弹接触硫芥气。
Clin Pract Cases Emerg Med. 2017 Sep 29;1(4):283-286. doi: 10.5811/cpcem.2017.5.34034. eCollection 2017 Nov.
3
Exposure to liquid sulfur mustard.接触液态硫芥。
Ann Emerg Med. 2001 Jun;37(6):653-6. doi: 10.1067/mem.2001.114322.
4
Sulfur mustard: cutaneous exposure.硫芥气:皮肤接触。
Clin Toxicol (Phila). 2005;43(1):55. doi: 10.1081/clt-48602.
5
[Mustard gas bombs found astray in the Faxaflói bay. Mustard gas: usage and poisonings].[在法克萨湾发现散落的芥子气炸弹。芥子气:用途与中毒情况]
Laeknabladid. 2009 May;95(5):359-65.
6
Notes from the field: Exposures to discarded sulfur mustard munitions - Mid-Atlantic and New England States 2004-2012.现场记录:2004-2012 年中大西洋和新英格兰各州废弃芥子气弹药接触情况。
MMWR Morb Mortal Wkly Rep. 2013 Apr 26;62(16):315-6.
7
Sulphur mustard injuries of the skin. Pathophysiology and management.皮肤芥子气损伤。病理生理学与处理
Toxicol Rev. 2003;22(2):111-8. doi: 10.2165/00139709-200322020-00006.
8
Efficacy of laser debridement with autologous split-thickness skin grafting in promoting improved healing of deep cutaneous sulfur mustard burns.激光清创联合自体中厚皮片移植促进深部皮肤芥子气烧伤愈合的疗效观察
Burns. 2002 Dec;28(8):719-30. doi: 10.1016/s0305-4179(02)00198-5.
9
Ocular injuries following sulfur mustard exposure: clinical characteristics and treatment.芥子气暴露后的眼部损伤:临床特征与治疗
Isr Med Assoc J. 2002 Jul;4(7):577-8.
10
Toxicology and pharmacology of the chemical warfare agent sulfur mustard.化学战剂芥子气的毒理学与药理学
Pharmacol Rev. 1996 Jun;48(2):289-326.

引用本文的文献

1
Analytical methods based on liquid chromatography for the analysis of albumin adducts involved in retrospective biomonitoring of exposure to mustard agents.基于液相色谱法的分析方法,用于分析涉及回溯性监测芥子气暴露的白蛋白加合物。
Anal Bioanal Chem. 2024 Apr;416(9):2173-2188. doi: 10.1007/s00216-023-04925-y. Epub 2023 Sep 13.
2
Deciphering the role of microRNAs in mustard gas-induced toxicity.解读微小RNA在芥子气诱导毒性中的作用。
Ann N Y Acad Sci. 2021 May;1491(1):25-41. doi: 10.1111/nyas.14539. Epub 2020 Dec 10.
3
Expression of Laminin 332 in Vesicant Skin Injury and Wound Repair.
层粘连蛋白332在水疱性皮肤损伤和伤口修复中的表达
Clin Dermatol (Wilmington). 2018;2(1).
4
Four sulfur mustard exposure cases: Overall analysis of four types of biomarkers in clinical samples provides positive implication for early diagnosis and treatment monitoring.四例硫芥暴露病例:临床样本中四种生物标志物的综合分析对早期诊断和治疗监测具有积极意义。
Toxicol Rep. 2014 Aug 13;1:533-543. doi: 10.1016/j.toxrep.2014.07.017. eCollection 2014.
5
Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review.沙林(GB,O-异丙基甲基磷酰氟)神经毒性:批判性综述。
Crit Rev Toxicol. 2016 Nov;46(10):845-875. doi: 10.1080/10408444.2016.1220916. Epub 2016 Oct 5.
6
Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard.一种非甾体双功能抗炎和抗胆碱能药物对硫芥诱导的皮肤损伤的治疗潜力。
Toxicol Appl Pharmacol. 2014 Oct 15;280(2):236-44. doi: 10.1016/j.taap.2014.07.016. Epub 2014 Aug 13.
7
Sulfur mustard induces an endoplasmic reticulum stress response in the mouse ear vesicant model.硫芥在小鼠耳肿胀模型中诱导内质网应激反应。
Toxicol Appl Pharmacol. 2013 Apr 15;268(2):178-87. doi: 10.1016/j.taap.2013.01.014. Epub 2013 Jan 26.
8
Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.芥子气类似物 2-氯乙基乙基硫醚诱导皮肤表皮细胞和成纤维细胞 DNA 损伤的机制。
Free Radic Biol Med. 2011 Dec 15;51(12):2272-80. doi: 10.1016/j.freeradbiomed.2011.08.020. Epub 2011 Aug 26.
9
Improved wound healing of cutaneous sulfur mustard injuries in a weanling pig model.断奶仔猪模型中皮肤芥子气损伤伤口愈合的改善
J Burns Wounds. 2006 Nov 8;5:e7.
10
Wound healing of cutaneous sulfur mustard injuries: strategies for the development of improved therapies.皮肤芥子气损伤的伤口愈合:改进治疗方法的开发策略。
J Burns Wounds. 2005 Jan 5;4:e1.