Nadkarni J J, De A K, Jhaver K J, Kamat M R
Immunology Division, Tata Memorial Hospital, Tata Memorial Centre, Parel, Bombay, India.
Neoplasma. 1994;41(2):123-8.
To assess the functional integrity of monocytes in patients with cervical carcinoma, cytotoxic potential of peripheral blood monocytes and their ability to secrete interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) after activation with different stimulating agents were studied. Comparable levels of monocyte-mediated cytotoxicity were observed in healthy donors and patients. The production of IL-1 and TNF-alpha by monocytes of healthy donors and patients was similar indicating no defect in monocyte functions in these patients.
为评估宫颈癌患者单核细胞的功能完整性，研究了外周血单核细胞在用不同刺激剂激活后的细胞毒性潜力及其分泌白细胞介素-1（IL-1）和肿瘤坏死因子-α（TNF-α）的能力。在健康供者和患者中观察到相当水平的单核细胞介导的细胞毒性。健康供者和患者单核细胞产生IL-1和TNF-α的情况相似，表明这些患者的单核细胞功能无缺陷。
