Di Mauro S, Arsena A, Salibra M, Belnome N A, Bartolo V, La Malfa G, Puglisi F
Cattedra di Chirurgia Generale e dell'Apparato Digerente, Istituto di Chirurgia Generale, Messina.
Minerva Chir. 1994 Jan-Feb;49(1-2):1-6.
The authors, after a dissertation on the aetiopathogenesis of "Barrett's oesophagus", dwell on the precancerous nature of this pathology involving the oesophageal-gastric junction. Its frequent association with cancer explains the necessity for an accurate follow-up in these patients: many investigations can be useful, the radiological study of oesophagus and stomach, manometry, pH-metry, but an irrefutable diagnosis can only be achieved through endoscopy, which makes possible a histological examination of the bioptic fragments. The authors also deal with the ideal therapeutic strategy and differentiate the cases in which the pharmacological therapy is more appropriate from those that need a surgical approach.
作者在论述了“巴雷特食管”的病因发病机制后，详述了这种累及食管胃交界处病变的癌前性质。它与癌症的频繁关联解释了对这些患者进行精确随访的必要性：许多检查可能有用，如食管和胃的放射学检查、测压法、pH测量法，但只有通过内镜检查才能做出无可辩驳的诊断，内镜检查使得对活检组织进行组织学检查成为可能。作者还探讨了理想的治疗策略，并区分了药物治疗更合适的病例和需要手术治疗的病例。
